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diagnosis oncology rheumatology algorithm differential lupus sle erythematosus lymphocytic mds myelodysplastic systemic thrombocytosis aclf acute aplastic arthritis bacilliformis bartonella blastomycosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
stem cell transplant ... progress to MDS or acute ... leukemia • Associated ... #diagnosis #management ... #treatment #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... , deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Allogeneic stem cell ... #treatment #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... months without treatment ... underlying liver disease ... #Chronic #Liver
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... life-threatening • Treatment ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... severe hemolytic anemia ... TREATMENT: ​• Acute ... Fever #diagnosis #management
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