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hematology algorithm causes workup classification thrombocytosis atlas bruising deficiency mcv microscopy morphology oncology purpura rbc reticulocyte secondary thrombocytopenia agglutinin alopecia
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Drugs, H pylori, Celiac ... hepcidin) • Others: Hemolysis ... disorders Dr. ... Deficiency #Causes #differential ... #diagnosis #anemia
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... extravascular) hemolysis ... - Structural: Celiac ... #ferritin #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Early Iron ... #Differential # ... #Causes #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
anemia. ... and laboratory diagnosis ... other testing (platelet ... are required for evaluation ... #anemia #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... with or without platelet ... Consider RBC membrane disorder ... #Anemia #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... • Celiac disease ... malignancy • Iron ... deficiency anemia ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... Unstable hemoglobin disorders ... elliptocytosis, Severe iron ... RBC #Morphology #differential ... #diagnosis #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Diagnosis Framework ... inflammation) • Iron ... , CKD • Hemolytic ... #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Count - Differential ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac
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