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diagnosis management hematology gastroenterology leukemia neurology algorithm cancer chronic classification differential encephalopathy evidence mds myelodysplastic 1 aki all anemia antipsychotic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... • Risks: infection ... transformation to acute ... only curative treatment ... #hematology #oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Treatment Schema ... for Standard-Risk ... Acute Lymphoblastic ... Cytarabine #ALL #Acute ... #timeline #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... malignancies Treatment ... Capillary leak syndrome ... cyclophosphamide) #Acute ... #AKI #Cancer #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Attempt if high risk ... Renal Failure Treatment ... management #hematology #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... grade lymphoma & Acute ... malignancies Treatments ... #TLS #oncology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute ... Any risk factor ... Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment ... development of Korsakoff syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
workup, including BM ... blood loss, Acute ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Severe trauma, Acute
Neurological Side Effects of Antipsychotic Drugs Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antipsychotic Drugs Acute ... patients at highest risk ... Elderly at greatest risk ... tremor ("rabbit syndrome ... months or years of treatment
Chronic Pancreatitis Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
fibroinflammatory syndrome ... , and/or other risk ... and recurrent acute ... osteoporosis • Risk ... gastroenterology #treatment
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