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Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... • Elevated D-Dimer ... • PTT: ↑ • D-Dimer ... Treat primary cause ... Coagulation #diagnosis #causes
Thrombotic Thrombocytopenic Purpura (TTP) vs Disseminated Intravascular Coagulation (DIC)
#Diagnosis #TTP #DIC #Comparison #Table #Laboratory #Findings #RebelEM
Intravascular Coagulation (DIC ... Diagnosis #TTP #DIC ... #Comparison #Table
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
D-dimer Plasma ... D-dimer is a product ... Elevated plasma D-dimer ... D-dimer has been ... age, which can cause
Common causes of sciatica. Disc herniation is the commonest cause. Spondylolisthesis can cause impingement #Anatomy #Pathophys
Common causes of ... Disc herniation ... the commonest cause ... Spondylolisthesis can cause
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
fibrinogen levels, D-dimer ... decompensated DIC ... Diagnosis #Honc #DIC
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation (DIC ... INR use PT D-dimer ... small vessels #DIC
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... platelet count, D-dimer
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation (DIC ... MAHA: TTP, HUS, DIC
Pathological Optic Disc Cupping

Note cup-to-disc ratio at least 0.8 (physiologic limit of 0.5).

Thinning of optic disc
Pathological Optic Disc ... Note cup-to-disc ... so that optic disc ... Usual cause is glaucoma ... Glaucoma causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... • Secondary Causes ... marrow disease - DIC ... Coagulation Defects: • DIC ... Purpura Fulminans (DIC