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rheumatology differential lupus erythematosus symptoms systemic treatment antibodies autoantibodies syndrome table algorithm ana anca antibody antineutrophil antinuclear associations behcet cardiology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
- ACR/VF 2021 Guidelines ... • Severe Disease ... • Non-Severe Disease ... #ACR2021 #Guidelines ... #algorithm #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... Anti-TSHR - Graves' disease ... connective tissue disease ... (TTG) - Celiac disease ... #Associations #diseases
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... (10%) : SLE +++ ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... connective tissue disease ... 90% • Anti-GBM disease ... Antineutrophil #antibodies #diagnosis ... diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... well as inner ear disease ... atherosclerotic disease ... most important diseases
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... Lupusreference #SLE ... autoantibodies #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... Inflammatory eye disease ... • Neurologic Disease ... #management #signs ... #disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease ... • Castleman's disease
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Systemic rheumatic diseases ... disease, drug reactions ... most important diseases ... (GRANULOMATOUS DISEASE ... HBV Kawasaki Disease
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