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differential workup lupus oncology syndrome algorithm anesthesia anesthesiology arthritis checklist dermatology erythematosus hemeonc hemophagocytic hlh intraoperative leukemia lymphohistiocytosis systemic thrombocytopenia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... hemorrhage) • Chronic ... myeloid leukemia (CML ... #Causes #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Positive in 60-80% of cases ... life-threatening • Treatment ... : Chronic disease ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... microglobulin Treatment ... workup #oncology #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... - Differential Diagnosis ... RA, SLE, PRV, Chronic ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... Disorders: • Chronic ... myeloid leukemia (CML ... #Differential #Diagnosis ... #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... test, ANA (e.g., SLE ... changes), high MCV ... not required in all ... #hematology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... Lupus #Nephritis #Management ... #treatment #management ... #rheumatology #
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... Primary: - CML ... Hypereosinophilic Syndrome - Chronic ... #Causes #hematology
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