17 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Cancer-treatment specific inducers ... (↑) and inhibitors ... Inducers of these ... or inhibitors of ... Interactions #Table #Pharmacology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... SSRIs #Serotonin #Inhibitors ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... SerotoninNorepinephrine #Inhibitors ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... • Calcineurin Inhibitors ... #differential #diagnosis ... pathophysiology #pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
heparin (UFH): Inhibits ... allosteric site) and induces ... anticoagulant that inhibits ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
un lymphatic Diagnostic ... endomyocardial biopsy Pharmacology ... : • ACE Inhibitors ... receptor-neprilysin inhibitors ... #heartfailure #diagnosis
Amiodarone Thyroid Complications
Amiodarone: 
 - iodine-rich, similar structure to T4, with half life up to 100d
up to 100d - inhibits ... • Amiodarone Induced ... • Amiodarone Induced ... endocrinology #diagnosis ... #pharmacology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
• Tolerance (reduced ... recreational activities reduced ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Psychiatry
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Carbonic Anhydrase Inhibitors ... disequilibrium syndrome • Diagnosis ... some overdoses Inhibitors ... syndrome • Lithium-induced ... Diuresis #Nephrology #Pharmacology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
irreversible • Drug induced ... #SideEffects #pharmacology ... #diagnosis #psychiatry