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hematology management differential signs erythematosus sle systemic ana antinuclear autoantibodies chronic classification cll comparison hemeonc hodgkins leukemia lymphocytic lymphoma monoclonal
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... likely it will be clinically ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
SLE-Related Auto-Antibodies ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs #symptoms ... #differential #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... : • Symptoms limited ... -70, RNP antibodies ... #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... [PCH] 3. ... Viral Infection Clinical ... hemolytic #anemia #hematology
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... Subcutaneous nodules, lupus ... pernio • Cardiac ... #Symptoms #Signs
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... - Pel-Ebstein ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... -15% If SLE is clinically ... erythematosus #diagnosis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
and Late Clinical ... radiculopathy, PN) • Cardiac ... - CSF + Lyme antibodies ... #diagnosis #signs ... #symptoms
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