46 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Syndrome Signs/Symptoms ... /Complications: ... sleep apnea, cor pulmonale ... Syndrome #genetics #pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... / Complications ... seizures) - Cardiac ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
to myosin and cardiac ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... lethargy, hematuria, cardiac ... with tetany or cardiac ... Syndrome #TLS #diagnosis
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Summary GERD: Diagnosis ... Laryngeal and pulmonary ... GERD - Complications ... Extraesophageal complications ... Reflux #Disease #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... , Schnitzler) Complications ... , DIC, TMA • Cardiac ... hepatitis • Pulmonary ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... fluid overload, PCC
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
nose deformity • Cardiac ... (UPC) ratio • Cardiac ... or serologies + symptoms ... #differential #diagnosis ... #management #treatment
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
30%; can be only symptom ... 3-12% • Cardiac ... incr in 27-75% • PCT ... 28% -> Incr risk complications ... Evaluation #Guide #Diagnosis
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical complications ... thiamine) Late: • Cardiac ... overload) Other Symptoms ... #Differential #Diagnosis ... #Pathophysiology