18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Management Summary Acute ... Acute myocarditis ... • Treatment: ... clinical evidence of cardiac ... clinical evidence of cardiac
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... - ACS, AKI, acute ... with tetany or cardiac ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine • MCC- acute ... • S - Saddle anesthesia ... Differential Diagnosis ... axial T1 and T2 Treatment ... #differential #diagnosis
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Management Summary Acute ... Acute myocarditis ... • Treatment: ... clinical evidence of cardiac ... clinical evidence of cardiac
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... (Acute Febrile ... Excellent response to treatment ... #Hematology #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute ... workup #oncology #hematology