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management rheumatology differential dermatology infectiousdiseases erythematosus lupus oncology sle american chagas sweet table trypanosomiasis acidosis activation acute adultonset ana anca
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology #
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... solid cancers • Systemic ... , DIC, TMA • Cardiac ... #diagnosis #management ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... scleroderma) - Anti-Scl ... cases • Sjögren syndrome ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary Acute Chagas Disease (8-12 weeks): • Mild: Malaise,
• Treatment: ... PCR not useful for ... clinical evidence of cardiac ... clinical evidence of cardiac ... #Management #Microbiology
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
• Typhoidal: Systemic ... Culture & GS, PCR ... Treatment: ... • Severe Disease ... infectiousdiseases #microbiology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... neuropathy) • Systemic ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... Cerebrovascular Disease ... permeability Diagnosis ... #cerebritis #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... thrombosis, VTE) • Cardiac ... ) Differential Diagnosis ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... 5% of patients Cardiac ... Cytopenias • Cardiac ... La, anti-Jo-1, SCL
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