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management differential syndrome chronic monoclonal cancer classification cll dermatology gammopathy hodgkins leukemia lymphocytic lymphoma nephrology aclf agglutinin aih aki algorithm
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Ig deposition disease ... #Significance #MGUS ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... symptoms - Pel-Ebstein ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... significance (MGUS ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology ... #diagnosis
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... inflammatory disease ... Excellent response to treatment ... count >10 x 10^3/pL ... #Hematology #Dermatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... rituximab (in clinical ... Complications #diagnosis ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... ’s lymphoma or acute ... #workup #oncology ... #hematology
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