407 results
Diagnostic Algorithm for Non–Small-Cell Lung Cancer (NSCLC). The upper portion of the algorithm shows the morphologic
oncogenic alterations: EGFR ... #NSCLC #PDL1 #NEJM
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
The protein complex mTORC1 is a convergence point for multiple signaling pathways that control cell growth
., INSR and EGFR ... TumorSuppressors #NEJM
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... CockcroftGault #EGFR
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Cetuximab and other EGFR ... in Na-KATPase, EGFR
Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
LowProteinDiet #GFR ... #NEJM
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
- 85% • Mean eGFR ... follow-up • eGFR
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
maximum dose eGFR ... recommended dose eGFR