12 results
diagnosis hematology differential causes algorithm hemolysis cold extravascular agglutinin analysis anemias atypical blood bruising classification clinical disease hus interpretation microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... uremic syndrome (HUS ... idiopathic) - Autoimmune ... #Hemolytic #Intravascular ... diagnosis #hematology #anemia
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... : • Autoimmune ... Hemolytic Anemias ... Hemolytic Anemias ... (AHAs) Nonimmune-mediated
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... Cold AIHA • Alloimmune ... - Hemolysis within ... anemia • ... MAHA (TTP, DIC, HUS
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Hemolytic Anemia ... Hemolytic Anemia ... #Hemolytic #Anemia ... hematology #diagnosis #comparison
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... → Sickle Cell anemia ... idiopathic, malignancy, autoimmune ... anemia (TTP, HUS ... #Anemia #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... , aHUS, mechanical ... elliptocytosis, autoimmune ... @ARUPLabs #Hemolytic ... #Anemia #Differential
Atypical HUS - Hemolytic Uremic Syndrome Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
Atypical HUS - Hemolytic ... shigatoxin mediated, aHUS ... minus diarrhea (autoimmune ... still present with anemia ... #aHUS #Hemolytic
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microangiopathic hemolytic ... anemia (e.g. ... DIC, TTP, HUS) ... Microspherocytes: Autoimmune ... hemolytic anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... IVIG infusion Intravascular ... • MAHA: TTP, HUS ... #Anemia #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... • Symptoms of anemia ... anemia • Cold ... CLL (older) • Autoimmune ... the RBCs causing intravascular
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