13 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Diagnosis Algorithm Signs ... of anemia and hemolysis ... Anemias (AIHAs) ... Anemias (AHAs)
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... AIHA • Anemia ... LDH • Anti-RBC autoantibodies ... #Anemia #diagnosis
Pathophysiology, Signs and Symptoms of Hemolytic Anemia

#Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, Signs ... and Symptoms of Hemolytic ... Anemia #Pathophysiology ... #Hemolytic #Anemia ... hematology #diagnosis #signs
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Anemia Warm Autoimmune ... Hemolytic Anemia ... Anemia: • Mechanism ... #Anemia #hematology ... #diagnosis #comparison
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
to 50X ULN • Autoantibodies ... heliotrope, shawl sign ... to 50X ULN • Autoantibodies ... : >50X ULN • Autoantibodies ... differential #diagnosis #comparison
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... Erythematosus #Diagnosis #autoantibodies ... #signs #symptoms
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
• Vitamin E - Haemolytic ... anaemia, ataxia ... paraesthesiae • Folate - Anaemia ... Vitamin B12 - Anaemia ... differential #diagnosis #signs
Pemphigus Vulgaris vs Bullous Pemphigoid - Comparison Table
Pemphigus Vulgaris
 • Epidemiology: Average age 40-60
 • Time
Bullous Pemphigoid - Comparison ... ruptured • Nikolsky sign ... • Antibodies: Autoantibodies ... Tense • Nikolsky sign ... Bullous #Pemphigoid #Comparison
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) Blood (75%): Anemia ... normochromic nomocytic or haemolytic ... erythematosus #signs
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
-DPG -> - hemolysis ... - anemia ... pathophysiology #symptoms #signs