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dermatology secondary erythematosus sle neurology oncology pruritus vasculitis activation ana anca antibodies antibody antineutrophil antinuclear antinxp2 antinxp2dm apml behcet bleeding
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Algorithm - Systemic ... BUN: • Chronic renal ... #generalized #dermatology ... Diagnosis #Algorithm
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... & renal involvement ... Treatment: • ... #rheumatology # ... management
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... (total 50, renal ... #differential # ... hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... CNS #neurology #rheumatology ... #management #treatment
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... ASA) • Renal Disease ... #Diagnosis #Algorithm ... #Causes #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
lupus erythematosus ... • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... #rheumatology #
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... BUN: • Chronic renal ... #generalized #dermatology ... Diagnosis #Algorithm ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Chronic renal ... • Nephrotic syndrome ... #Differential # ... Diagnosis #Algorithm ... #causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... Hepatosplenomegaly and generalized ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Diagnosis Algorithm ... Celiac, IBD) • Renal ... #Diagnosis #Algorithm ... #endocrinology ... #causes #pediatrics
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