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diagnosis erythematosus sle syndrome systemic treatment dermatology differential hepatology summary table workup abnormal activation adultonset algorithm ana antinuclear antinxp2 antinxp2dm
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... thrombocytopenia • Liver function ... tests ↑ AST ↑ ALT ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Ledderhose disease (plantar fibromatosis) on POCUS Rheumatology @Rheumatology #Ledderhose #disease #POCUS #MSK #ultrasound #clinical #plantar #fibromatosis
Ledderhose disease ... fibromatosis) on POCUS Rheumatology ... @Rheumatology ... #POCUS #MSK #ultrasound ... #clinical #plantar
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 Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Evolution: Chronic disease ... #Summary #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... decreased glycosylated fraction ... #diagnosis #management ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... -15% If SLE is clinically ... suspected, tests ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... including liver function ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... mellitus; USS, ultrasound ... Abnormal #Algorithm #Hepatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
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