60 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: • Infections ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment ... Algorithm for MAS / HLH ... Lymphohistiocytosis #Management ... #Treatment #Algorithm ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Non-HCV infectious ... Diagnosis, causes and management ... neuropathy Treatment ... Cryoglobulinemia #Vasculitis #Rheumatology ... Cryoglobulinemic #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SLE], AOSD) • Infection ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... associated with infection ... autoimmune disease, treatment ... #Treatment #management ... #hematology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... • Autopsy PCR ... Treatment: • ... Hantavirus #diagnosis #management ... #treatment #microbiology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... risk-stratification • Risks: infection ... acute leukemia Management ... only curative treatment ... #treatment #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... megaloblastic anemia Treatment ... Anemia #diagnosis #management ... #treatment #hematology
Listeriosis Summary - Listeria Monocytogenes
Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming
Risk
Pregnancy • CNS infection ... Gastroenteritis) • PCR ... ) • CSF (CNS Infection ... Monocytogenes #diagnosis #management ... infectiousdiseases #treatment