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diagnosis differential nephrology dka endocrinology pathophysiology algorithm causes diabetes management urine casts comparison criticalcare crystals defects diabetic diabeticketoacidosis dipstick disorders
Urinalysis & Urine Sodium Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
urine #UNa #casts #glucosuria
Polyuria - Differential Diagnosis Solute Diuresis • Na intake/saline • Glucosuria: Hyperglycemia, SGLT-2 inhibitors • Urea: Exogenous
intake/saline • Glucosuria
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Hyperglycemia → Glucosuria
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
., mannitol, glucosuria
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Cells Renal glucosuria
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Glucosuria causes
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
> 250 mg/dl or Glucosuria ... 250 mg/dl and Glucosuria
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
• Polyuria, Glucosuria
Urine Specific Gravity - Interpretation Specific Gravity = Density of urine / Density of water SG close to
• Cirrhosis • Glycosuria
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption •
Inhibitors • Kidney: Glycosuria
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