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causes hematology algorithm management anemia hyperkalemia iron heartfailure nutrition potassium high infectiousdiseases nephrology pharmacology clinical hepatology hfref microbiology pathophysiology table
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... fragmentation hemolysis ... • Severe B12 deficiency ... • Mechanical hemolysis ... #hemolysis
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... think of immune hemolysis ... , hemolytic transfusion ... Intrinsic #Extrinsic #Differential ... #Diagnosis #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... immune-complex hemolytic ... malformations #Hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Intravascular Hemolysis ... Microangiopathic hemolytic ... purpura (TTP), Hemolytic ... G6PD deficiency)
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... DAT (-) → G6PD Deficiency ... Immune mediated hemolysis ... Microangiopathic hemolytic ... UnremarkableLab #Hemolytic
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... • Blood smear: Differential ... Antibody #Autoimmune #Hemolytic ... #management #treatment
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... • Early Iron Deficiency
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... venipuncture • Hemolysis ... edema • Jaundice/Hemolytic ... cell lysis: - Hemolysis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
bloodstream Hemolysis ... : • Hemolytic ... Microangiopathic hemolytic ... anemia, PNH, immune hemolysis ... myelofibrosis • Hemolysis
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