22 results
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Suspected Celiac ... and symptoms of celiac ... disease • Iron-deficiency ... unresponsive to treatment ... Diagnosis #Algorithm #gastroenterology
Folate Deficiency - Causes of Decreased Folic Acid
↓ Intake: Diet, Age, Alcohol
↑ Demand: Pregnancy, Infancy, Hemolysis,
Folate Deficiency ... Pregnancy, Infancy, Hemolysis ... ↓ Absorption: Coeliac ... drkeithsiau #Folate #Deficiency
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... hepcidin) • Others: Hemolysis ... drkeithsiau #Iron #Deficiency
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
Diagnostic Tests for Celiac ... negative with IgA deficiency ... patients with IgA deficiency ... patients with IgA deficiency ... Reflects response to treatment
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency ... extravascular) hemolysis ... - Structural: Celiac ... Zinc excess or deficiency ... , Copper deficiency
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Evaluation of Iron Deficiency ... diagnose iron deficiency ... tests Test for celiac ... management #Iron #Deficiency ... workup #diagnosis #gastroenterology
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Bleeding, Edema, Celiac ... cancer) #Iron #Deficiency
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
disorders • Celiac ... effect following treatment ... malignancy • Iron deficiency
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac
Causes of Iron Deficiency - Differential Diagnosis Algorithm
 • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Intravascular hemolysis ... of absorption): Celiac ... tony_breu #Iron #Deficiency