16 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
mutation) that alter ... yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
(Composed of T-helper ... & inflammatory cells ... dysrhythmias • Ophthalmologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... polymorphisms alter ... various inflammatory cells ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
The whirlpool sign of acute testicular torsion. Always nice to clinch the diagnosis.

Dr. Howard T Heller
The whirlpool sign ... to clinch the diagnosis ... #whirlpool #sign ... testicular #scrotal #pocus ... #clinical #ultrasound
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... removal of these cells ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
PO4 and Mg into cells ... Constipation - MSK ... Refeeding #Syndrome #diagnosis ... #pathophysiology ... #symptoms #signs
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
joints to the pelvis ... -> The pelvis is ... #Scoliosis #pathophysiology ... #msk #diagnosis ... #signs #symptoms
Intramuscular Calf Hematoma on POCUS
80 y/o older man. CAD + DAPT.  Working on fishing boat.
Calf Hematoma on POCUS ... 80 y/o older man ... POCUS with no DVT ... signs, but demonstrating ... #msk #ultrasound