14 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... : • Infections ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Systemic lupus erythematosus ... SLE], AOSD) • Infection ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... Systemic lupus erythematosus ... , Sarcoidosis, HLA-B27 ... rare), Idiopathic Infectious ... Differential #Diagnosis #rheumatology
Pediatric Button Battery Ingestion
Most serious BB ingestions are not witnessed. Therefore, have a low threshold for
Pediatric Button ... Battery Ingestion ... Button batteries cause ... #toxicology #diagnosis ... #management #Pediatrics
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
steroids • In mild cases ... associated with infection ... Options for severe cases ... #Treatment #management ... #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Diagnosis and Management ... , Cough • +/-Nausea ... cæxist with other infections ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... History of EBV infection ... LN on alcohol ingestion ... classification #hematology ... #oncology #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
7) Always in case ... Unexplained fever, when infection ... including in children (pediatric ... #system #erythematosus ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Triggers: ▪ Infections ... Pathophysiology ... underlying trigger: Infections ... #Hematology #HemeOnc