23 results
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
slurred speech, weakness ... Rare unless co-ingestion ... with other CNS ... Benzodiazepines #Psychiatry #Pharmacology ... #pathophysiology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Differential Diagnosis Algorithm ... Anemia • Chronic Infection ... Dystrophy • Statin ... #Neurology #Differential ... #Diagnosis #Algorithm
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
pulmonary etc) • CNS ... Vasculitis • Infectious ... Myeloma/amyloid • Infectious ... toxins: Steroids, Statins ... Differential #Diagnosis #neurology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
damage, acute weakness ... Facial nerve (7th CN ... associated with viral infections ... #Bells #Palsy #neurology ... #anatomy #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... Lupus Cerebritis Induction ... Secondary prevention (statin ... #neurology #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... response preceding infection ... : Starts in legs ... Treatment: • Plasmapheresis ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... infections result ... Antimicrobial treatment ... altered mental status ... InfectiousDiseases #Neurology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Differential Diagnosis Algorithm ... Panhypopituitarism Treatment ... CRF) • Infection ... Anorexia Nervosa • CNS ... Differential #Diagnosis #Algorithm
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Differential Diagnosis Algorithm ... Altered mental status ... brain lesion • CNS ... infection (e.g. ... #neurology #PHANTOMS
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... of generalized status ... hyperthermia, myocardial infarction ... #Management #Neurology ... Refractory #Seizures #Algorithm