34 results
diagnosis differential oncology management infectiousdiseases algorithm syndrome aids chronic dermatology hiv lymphocytic mds myelodysplastic pathophysiology thrombocytopenia thrombocytosis treatment vasculitis workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... pain, bleeding, infections ... bruising, bleeding, infection ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... (CBC with Lymphocytes ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Lymphocytosis on CBC ... surface molecules: CD5 ... leukemia #CLL ... workup #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Myelofibrosis Infectious ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm Infectious ... Viral (EBV) • Parasitic ... • Lymphoma • Leukemia ... Disease • Sickle Cell ... #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Diabetes/DKA Infections ... : • helminth infections ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... ITP • SLE • CLL ... Vasculitis • Infection ... #Hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... , myiasis) - Parasites ... Primary: - CML ... Acute Eosinophilic Leukemia ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute infection ... Chronic myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... salmonella, ...), Parasites ... lymphoma, B-cell ... Drugs, Unknown cause ... treatment #summary #rheumatology
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