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diagnosis differential autoantibodies dermatology comparison hematology management medications myopathy acute antibodies antihypertensive antinuclear autoimmune autoinflammatory behcet bloodpressure causes cold connectivetissuediseases
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Autoantibodies #Associations ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... PSS: Sjogren syndrome ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... searched for when ANA ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis #rheumatology ... #table #ANA
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
of life Causes and ... clinical associations ... liquids The onset and ... Urticaria #diagnosis #rheumatology ... #comparison #table
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... focal lesions on MRI ... plasmacytoma, POEMs syndrome ... autoimmune diseases ... MGUS #diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... Asia • HLA-B51 association ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... signs #symptoms #rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
alveolitis, ear and ... thromboembolic disease ... (MDS) and/or ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
cause of renal disease ... CT or MRI scan of ... • Cushing’s syndrome ... Mineralocorticoid excess syndromes ... Screening #Workup #table
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... syndrome • Hyponatremia ... • Liddle syndrome ... New York Heart Association ... #Medications #Table
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