32 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
histoplasmosis) • Milk (calcium ... )-alkali syndrome ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... 4.6 mg/dL • Calcium ... - Calcium gluconate ... #TumorLysis #Syndrome ... #TLS #diagnosis
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... Diagnosis Framework ... #endocrinology ... #calcium
Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... @NEPHKIDS1 #Hypocalcemia ... Workup #Algorithm #differential ... #diagnosis #endocrinology ... #causes #calcium
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Differential Diagnosis ... Autosomal Dominant Calcium ... #Differential # ... Diagnosis #Algorithm ... #Endocrinology
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
dihydroxyvitamin D can help differentiate ... Hypoparathyroidism - Calcium-sensing ... Hyperparathyroidism #Diagnosis ... #Endocrinology ... #Differential
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Hyperparathyroidism • Hypercalcemia ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology ... Classification #Diagnosis
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... Bony Mets - Calcium ... #Differential # ... Diagnosis #Algorithm ... #causes #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... : • Pathophysiology ... hydration - Hyperkalemia ... #TLS #diagnosis
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... - Calcium Sequestration ... - DiGeorge Syndrome ... #endocrinology ... #differential #algorithm