61 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
failure, Addison's disease ... Granulomatous diseases ... )-alkali syndrome ... differential #diagnosis #calcium ... #high #endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
PTH) Effect in Calcium ... and Phosphorus Calcium ... - Net Effect Hypercalcemia ... #Phosphorus #pathophysiology ... #endocrinology
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Hypocalcemia Laboratory ... Hypoparathyroidism - Calcium-sensing ... Chronic kidney disease ... #Hypocalcemia ... Hyperparathyroidism #Diagnosis #Endocrinology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... Activation: Liver disease ... , Kidney Disease ... - Calcium Sequestration ... Diagnosis #Management #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... Hepatobiliary Disease ... Chronic Kidney Disease ... Algorithm #Phosphate #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Granulomatous disease ... #Hypercalcemia ... Differential #Diagnosis #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Granulomatous Disease ... Bony Mets - Calcium ... Algorithm #causes #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Autosomal Dominant Calcium ... Metastatic Bone Disease ... Granulomatous Disease ... Other • Excess Calcium ... Diagnosis #Algorithm #Endocrinology
Hypocalcemia - Regulation and Pathophysiology 

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Regulation #Pathophysiology #endocrinology #calcium
Hypocalcemia - Regulation ... and Pathophysiology ... @NEPHKIDS1 #Hypocalcemia ... #endocrinology ... #calcium
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Hyperparathyroidism: ↑→PTH, ↑Calcium ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology