159 results
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Diabetes Insipidus ... vs Syndrome of ... Table Diabetes Insipidus ... #Diabetes #Insipidus ... Comparison #Table #Pathophysiology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Algorithm - Diabetes Insipidus ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Central diabetes insipidus ... Nephrogenic diabetes insipidus ... Causes #nephrology #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
limb Gitelman syndrome ... tubule Liddle syndrome ... cell epithelial sodium ... of epithelial sodium ... Nephrogenic diabetes insipidus
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Euvolemic: Diabetes insipidus ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Insensible losses Sodium ... Central Diabetes Insipidus ... Nephrogenic Diabetes Insipidus
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Pathophysiology
Pathophysiology of The Nephron - Electrolyte and Water Exchange

The nephron — electrolyte and water exchange. 
180
Pathophysiology ... 26000 mmol of sodium ... 60—180 mmol of sodium ... #Pathophysiology
Pathophysiology of hepatorenal syndrome (HRS)

doi: 10.1136/bmj.m2687 

#hepatorenal #syndrome #HRS #Pathophysiology #nephrology
Pathophysiology ... of hepatorenal syndrome ... #hepatorenal #syndrome ... #HRS #Pathophysiology