41 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... common • Imaging: CXR ... initiation • Differential ... • Supportive Care
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... - ACS, AKI, acute ... : • Pathophysiology ... #TLS #diagnosis
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Hypophosphatemia - Differential ... Diagnosis Algorithm ... , Acute Respiratory ... Carboxymaltose, CAR-T ... #Diagnosis #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Responsive to Treatment ... Treated Like Acute ... Classification #pathophysiology ... #Hematology #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Diagnosis: Viral ... care support, Transfer
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Blood cultures • CXR ... early disease) • CXR ... Clindamycin in case
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... At least 3 of (Acute ... fluid balance, and CXR ... Reactions #hematology #diagnosis
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Pulmonary Edema - Differential ... Diagnosis Framework ... NCPE Pathophysiology ... ischemic changes CXR ... respiratory distress syndrome
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... hyperparathyroidism Treatment ... • Arrhythmias are ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- Summary Acute ... Guillain-Barre Pathophysiology ... Guillain-Barre Clinical ... variants: (1) acute ... #treatment #neurology