29 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute ... Conservative/supportive care ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Presentation: Subacute-Acute ... : DAH, acute febrile ... , Anaphylaxis, Acute ... #oncology
Pharmacotherapy for Migraine Prophylaxis 

Who is indicated for migraine prophylaxis? Patients who experience more than 3
despite appropriate acute ... treatment, or those ... who are intolerant ... contraindications to acute ... Medications #Table #Pharmacology
Sexually Transmitted Infections - Common Outpatient Treatments 
Chlamydia 
 - Azithromycin 1 g PO once
Common Outpatient Treatments ... conditions including acute ... the first-line treatments ... STIs #Outpatient #Treatment ... #Management #Pharmacology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... • Supportive care ... progress to MDS or acute ... diagnosis #management #treatment ... #hematology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
therapies in critical care ... ventilation, ARDS acute ... InfectiousDiseases #Infections #Pharmacology ... #Management #Treatment
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Classify severity Treatment ... - Acute Bleeding ... multidisciplinary care ... by a hemophilia treatment ... #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs are substrates ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
tumour B cells are ... Responsive to Treatment ... Treated Like Acute ... growth, response to treatment ... pathophysiology #Hematology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
- Cuteanous: acute ... agranulocytosis [rare ... to very rare: due ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology