29 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
risk-stratification • Risks: infection ... transformation to acute ... Conservative/supportive care ... Management #treatment #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... • Supportive care ... progress to MDS or acute ... management #treatment #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
granules which are ... translocation • Acute ... thrombocythemia • Acute ... : • helminth infections ... Diagnosis #causes #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... (bacterial), acute ... Like in this case ... • Acute = Viral ... #Joint #Pain #MSK
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
diutinum • A rare ... children with acute ... rash observed in acute ... multiforme • Acute ... differential #diagnosis #dermatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
: DAH, acute febrile ... Differential Diagnosis: Infection ... , Anaphylaxis, Acute ... • Supportive Care ... diagnosis #management #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
hemorrhage, which are ... - Trauma - Infection ... Disseminated gonococcal infection ... Algorithm #Causes #dermatology ... #physicalexam
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Framework What are ... Some pustules are ... sterile and are ... Acute generalized ... Differential #Diagnosis #Dermatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
tumour B cells are ... Potential For Cure ... Treated Like Acute ... Amy Chung, MD, MSc ... pathophysiology #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
It is rare in presentation ... can mimic common infections ... presents as an acute ... insulting agent are ... management #treatment #hematology