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diagnosis treatment anemia blood differential intravascular liver product syndrome aflp aplastic artificial basophilia basophils bleeding coagulation comparison complications dic disseminated
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Thresholds in Critical Care ... NEJM 1999 - ICU FOCUS ... unnecessary and cause ... Transfusions are ... #Thresholds #Hematology
Transfusion Reactions - Summary Cheatsheet • Hemolytic Reaction • Febrile Reactions • Transfusion Related Acute Lung
Transfusion Reactions ... • Febrile Reactions ... Related Acute Lung ... #Reactions #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Reaction ... Related Acute Lung ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Reaction ... Related Acute Lung ... #diagnosis #management ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... At least 3 of (Acute ... #Reactions #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... reaction, Paroxysmal ... lactam antibiotics are ... Extravascular #Causes ... differential #diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
granules which are ... during an allergic reaction ... translocation • Acute ... thrombocythemia • Acute ... #hematology #basophils
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
• Supportive care ... (transfusions, ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... transformation to acute ... Conservative/supportive care ... #treatment #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... severity Treatment - Acute ... multidisciplinary care ... #treatment #hematology
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