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diagnosis causes dermatology liver algorithm blood oncology product treatment aflp anemia apml basophilia basophils bleeding bruising cellulitis chemistry differentiation dress
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... , POEMS • Reaction ... Diagnosis #Algorithm #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... granules which are ... during an allergic reaction ... translocation • Acute ... Diagnosis #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Conservative/supportive care ... Myelodysplastic #Syndrome ... #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... lactam antibiotics are ... Extravascular #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... - APLS • Acute ... fever • Drug reactions ... #Diagnosis #hematology
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics Cellulitis: Deep skin and subcutaneous fat infection Pseudo
Pseudocellulitis - Differential ... avoid allergic reactions ... substantial health care ... • Gout • Acute ... • Compartment syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... • Supportive Care ... APML #diagnosis #management ... #hematology #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Resolution > 15 days Differentials ... • SJS/TEN • Acute ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... • Acute Hemolytic ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... infiltration) Differential ... Support - Critical care ... Liver #Pregnancy #hepatology
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