18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Conservative/supportive care ... Myelodysplastic #Syndrome ... #treatment #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of ... cells that are ... formed or don’t work ... Workup: • Complete ... #diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Transfusions: Cellular blood ... components are ... disorders (DiGeorge Syndrome ... #Indications #Hematology ... #BloodBank #Management
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Diagnosis and Management ... : • 2 sets of blood ... typically part of the workup ... Purulent Arthritis Syndrome ... afebrile • Acute
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Supportive Care ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
large numbers and are ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... the peripheral blood ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Noninflammatory • Bloody ... tumor • Non-bloody ... Like in this case ... Joint #Pain #MSK #rheumatology ... #approach #workup
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... insulting agent are ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology