49 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... infarction, Severe trauma ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... Conservative/supportive care ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... • Mechanical Trauma ... ) - HELLP syndrome ... lactam antibiotics are ... #hematology #anemia
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
hyperviscosity syndrome ... Pelvic/penile trauma ... t be tested or are ... #Priapism #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Solar purpura - Trauma ... Gardner-Diamond syndrome ... #hematology #rheumatology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
thrombophilias are ... (e.g. surgery, trauma ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... Cryoglobulins are ... Hyperviscosity syndrome ... Cryoglobulinemia #Vasculitis #Diagnosis ... #Rheumatology #
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... other forms of trauma ... Brown-Séquard Syndrome ... herniation - Trauma ... #differential #diagnosis
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
schistocytes which are ... Schistocytes are ... In the right photo ... is mechanical trauma ... hemolytic- uremic syndromes
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in severe • Rare ... • Supportive Care ... Differentiation #Syndrome ... #management #hematology