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diagnosis management erythematosus systemic ana antinuclear druginduced hematology neurology physicalexam activation anisocoria antibodies autoantibodies cerebritis chronic classification cll cns comparison
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... constitutional symptoms • Treatment ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #table #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
is clinically suspected ... RibP peptide) are ... overlap syndromes ... erythematosus #diagnosis #rheumatology ... #table #ANA
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... Erythematosus #SLE ... CNS #neurology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... - If present, are ... life-threatening • Treatment ... Management #Summary #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... (SLE) General: ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... ), Sjogren's Syndrome ... What diseases are ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... Treatment: • Corticosteroids ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... diseases: - 10% SLE ... (e.g. systemic lupus ... erythematosus (SLE ... classification #rheumatology
Horner's Syndrome on Physical Exam A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... or induced by treatment ... surgery; as in our case ... The video highlights ... #clinical #video
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 Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
large numbers and are ... non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... microglobulin Treatment ... • Richter’s Syndrome
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