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hematology diagnosis causes cancer classification leukemoid leukocytosis macrocytic mds microcytic morphologic myelodysplasia myelodysplastic oncology syndromes wbc
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... inflammation) • Iron ... Normocytic ( ... #MCV #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... to Anemia - Differential ... Diagnosis Algorithm ... Acute Bleed - Normocytic ... Reticulocytes, MCV
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Platelets #Differential
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... Microcytic" • Iron ... 80 - 96 fL - "Normocytic ... #differential # ... diagnosis #causes #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... ) - Differential ... • Early Iron ... Deficiency #Normocytic ... #Anemia #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... effect following treatment ... malignancy • Iron ... deficiency anemia ... #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Approach to Leukocytosis ... - Differential ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... #hematology #WBC
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(cell) volume (MCV ... (up to 100) = normocytic ... erythropoietin (EPO), iron ... substrate (e.g. iron ... #Workup #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... rings of excess iron ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
approaches. ... disease tolerate anemia ... toxicity from iron ... neutrophils or platelets ... #algorithm #hematology
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