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algorithm management liver oncology albumin ascites biliary cirrhosis gradient lfts monoclonal saag vascular abnormal aortoenteric apml arterial bariatric bile bypass
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... dL: Cirrhosis, Late ... albumin #gradient #hepatology ... #differential # ... diagnosis #algorithm
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG) SAAG ≥ 1.1: • Cirrhosis • Portal
Ascites Differential ... Diagnosis Table ... thrombosis • Late ... • Nephrotic syndrome ... Gradient #SAAG #hepatology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... anemia" • HELLP syndrome ... Catastrophic APLS BCM IM ... #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... proliferation rate ... #TLS #diagnosis ... #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... DADS-M, Sporadic, late-onset ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... and hepatorenal syndrome ... #Diagnosis #causes ... #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... • Jaundice (later ... bile ducts Differential ... #workup #hepatology
Bile Duct Paucity - Differential Diagnosis • Genetic: Alagille syndrome, Trisomy 21, Williams syndrome, Peroxisomal disorders
Duct Paucity - Differential ... Diagnosis • Genetic ... Biliary atresia (late ... Paucity #biliary #hepatology ... Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome ... #management #hematology
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