21 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Cirrhosis - Diagnosis Algorithm ... Symptoms: Fatigue ... , Pruritus, Right ... of autoimmune disease ... #hepatology
Atrial Fibrillation Overview

Symptoms:
Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

1. Why?
Cardiac:
• Valvular heart disease
•
Fibrillation Overview Symptoms ... Palpitations, light-headedness ... Rate Control • ... Fibrillation #Cardiology #Management ... #Algorithm
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... splenomegaly, abnormal neurology ... , back pain Haematology ... - Sickle cell disease ... #Limping #NWB #Algorithm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... of liver disease ... gastroenterology #algorithm ... gastroenterology #hepatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... Ig deposition disease ... (light chain vs ... Differential #Diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... TLS #diagnosis #management ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... • Jaundice (later ... but elevated as disease ... diagnosis #workup #hepatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... • Treatment algorithms ... von Willebrand disease ... PV #Diagnosis #Management ... Summary #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
→ fevers, night ... chemotherapy for low-risk disease ... Constitutional symptoms ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management