21 results
Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC ScoreA Systematic Review and
Necrotizing Soft Tissue Infection ... #Diagnosis #EBM ... LRINEC #Accuracy #Sensitivity ... #Specificity
Fernando SM et al. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in
With Suspected Infection ... pubmed/29404582 #EBM ... Screening #Sepsis #Sensitivity ... #Specificity #Metaanalysis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... 100%, specificity ... Demyelinating disease caused ... effect/Edema • EBV ... 92% and specificity
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... Galactomannan sensitivity ... associated with low sensitivity ... and low specificity ... considered in certain cases
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& seizures are late ... and hematologic infection ... widespread infection ... bacteremia are late ... peds #pediatrics #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... Drugs, Unknown cause
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... CSF has a 99% sensitivity ... and specificity ... and specificity
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Lung Abscess Pathophysiology ... CXR upright or lat ... #differential #causes
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Sensitivity (rule ... Specificity (rule ... FN) Higher specificity ... PPV Higher sensitivity ... alters recall Late-look
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... monophasic Pathophysiology ... Hyperreflexia develops later ... causes need to ... Brucellosis - Dengue, EBV