9 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Direct renin ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
ARBs Decreased Renin ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... Inhibition of Renin ... hyporenin hypoaldo, hyperkalemic ... KidneyDisease #nephrology ... #Effects #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... Decreased heart rate ... - Hyperkalemia ( ... #Pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... ) -> Increased Sensitivity ... inflammation #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Glomerular Filtration Rate ... • AKI High Renin ... • NSAlDs #Hyperkalemia ... IntercellularShift #Nephrology
Macula Densa Pathway - Physiological Pathways, Feedback Loops, and Pharmacological Regulation of the Renin-Angiotensin-System

#MaculaDensa #Pathophysiology #Nephrology
Regulation of the Renin-Angiotensin-System ... #MaculaDensa #Pathophysiology ... #Nephrology #Renal ... #Pharmacology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... with hypertension being ... sequences improve sensitivity ... diagnosis #management #neurology