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differential management erythematosus lupus systemic classification joint oncology symptoms arthritis syndrome disease leukemia msk testing treatment vasculitis activation algorithm anemia
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... thin smear • Signs ... Clinical findings of PAN ... values supporting hematologic ... #diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Travelers from ... Frequent Differential Diagnoses ... without localizing signs ... • Abdominal pain ... #differential #diagnosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Malar rash • SLE ... • Rheumatic fever ... #differential #diagnosis ... #rheumatology
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Diagnostic criteria ... 30mm length) • Fever ... • Abdominal pain ... Enterocolitis #Diagnosis ... #criteria #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Vasculitis (e.g., PAN ... conditions #joint #pain ... #differential #diagnosis ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Constitutional domain: Fever ... pericarditis • Hematologic ... #SLE #Systemic ... Erythematosus #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... • Rheumatic fever ... arthritis • SLE ... #MSK #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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