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management rheumatology hlh lymphohistiocytosis syndrome dermatology disease oncology classification differential kawasaki pediatrics summary sweet workup activation acute adult algorithm anemia
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Travelers from ... Frequent Differential Diagnoses ... without localizing signs ... #differential #diagnosis ... #tropical #travel
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hemophagocytic Lymphohistiocytosis ... Clinical Features: Fever ... : • Fever • Splenomegaly ... EricsMedicalLectures/ #HLH #Hemophagocytic ... #hematology #criteria
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Criteria for Patients Under Investigation for 2019 Novel Coronavirus (2019-nCoV) / COVID-19 Fever or signs/symptoms of lower
Criteria for Patients ... AND A history of travel ... AND A history of travel ... nCoV2019 #COVID19 #Criteria ... #Diagnosis #Wuhan
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : HLH signs and ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... Histopathologic criteria ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Symptomatic anemia Diagnosis ... if neutropenic fever ... #management #treatment ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... • Clinical: fever ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
Hemophagocytic Lymphohistiocytosis ... (HLH) Diagnostic ... Criteria - 2004 ... following: - Fever ... #Criteria #Hematology
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