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management differential oncology rheumatology hemophagocytic hlh leukemia lymphohistiocytosis rash algorithm aplastic chronic cll erythematosus hemeonc infections infectiousdiseases lupus lymphocytic sle
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... if neutropenic fever ... #diagnosis #management ... #treatment #hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
the Nikolsky sign ... staphylococcal scalded skin syndrome ... and toxic shock syndrome ... or Nikolsky sign ... #Diagnosis #Dermatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Leptospirosis ... Brucellosis Faget's Sign ... • Malaria • Leptospirosis ... #Differential #Diagnosis
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Clinical Manifestations ... of Serotonin Syndrome ... sounds, RUQ pain • Dermatologic ... : Tachycardia, Fever ... #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... recurrent infections/fevers ... #oncology #hematology ... #diagnosis #management
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... mountain spotted fever ... #hematology #rheumatology ... #nonpalpable #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH) Clinical ... Features: Fever ... : ↑↑ ferritin, Anemia ... 8 criteria: • Fever ... #hematology #criteria
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: Fever ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... Stevens-Johnson Syndrome ... differentiating between the diagnosis ... #TEN #Dermatology ... PhysicalExam #Video #Clinical
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