49 results
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Frequent Differential Diagnoses ... infection Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
(SLE) - Typical ... Signs/Symptoms ... Alopecia, Fever, ... #Signs #Symptoms ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fever (50%), Depression ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Workup • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... • Rheumatic fever ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Constitutional domain: Fever ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis ... #rheumatology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Constitutional: Fever ... neuropathies • Skin ... Subcutaneous nodules, lupus ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #Systemic #Lupus ... #Summary #diagnosis ... #rheumatology #