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management hemeonc syndrome anemia chronic cll dermatology hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis workup apml classification clinical differential differentiation emergencies fuo
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Frequent Differential Diagnoses ... infection Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Workup • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... if neutropenic fever ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... anemia Treatment ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... → fevers, night ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... , breast CA - Hematologic ... Treatment: - Systemic ... #dermatology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... : >3 symptoms, or ... #management #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Neutropenic fever ... : - Fever + ANC ... syndrome): - Hematologic ... #HemeOnc #Diagnosis
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