30 results
differential causes oncology workup dermatology management hemolytic pancytopenia rheumatology treatment erythematosus infections infectiousdiseases leukemia lupus mds myelodysplastic neutropenia rash sle
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
- Differential Diagnosis ... Algorithm Sequestration ... Myelofibrosis Stem cell ... • Toxins • Aplastic ... Anemia • Myelodysplasia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... if neutropenic fever ... #Anemia #diagnosis ... management #treatment #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Anemia • Toxic ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Hematology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... ’ algorithm • ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Presentation: • Fever ... recurrent infections/fevers ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... • Neutropenia, anemia ... aplasia • ITP ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Algorithm #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... Allogeneic stem cell ... Management #treatment #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... Algorithm Hereditary ... DAT (-) → Sickle Cell ... HTN) • Recent travel ... /Fevers, DAT (-)
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