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differential management rheumatology dermatology erythematosus hemeonc infections infectiousdiseases leukemia lupus pain sle systemic treatment aplastic arthritis chronic classification cll emergencies
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Frequent Differential Diagnoses ... infection Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Workup • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Diagnosis: • Pancytopenia ... if neutropenic fever ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... Management #treatment #hematology ... #oncology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... • Leptospirosis ... Brucellosis Faget's Sign ... #Differential #Diagnosis
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
region Viral Syndromes ... ; dengue shock syndrome ... Infections: • Leptospirosis ... No hemolytic anemia ... and myalgias, symptoms
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
brief interval symptom ... -14 days): • Fever ... rash • Others: nausea ... Biphasic #Phases #Diagnosis ... #Illness #Signs
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... death Neutropenic Fever ... #differential #diagnosis
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
within morulae Signs ... and symptoms: ... after bite • Fever ... immature forms) • Anemia ... Anaplasma #Infection #diagnosis
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