42 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... nose chondritis, skin ... Abnormalities: macrocytic anemia ... Autoinflammatory #Somatic #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #hematology #oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... #hematology #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Headaches • Pale skin ... #oncology #hematology ... #diagnosis #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
- Diagnosis Diagnostic ... vasculitis - Skin ... test Most Common Clinical ... Wide variety of skin ... #criteria #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule ... #Rheumatology # ... diagnosis #management
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... cryoglobulinemia vasculitis Clinical ... manifestations - Skin ... Cryoglobulinemia #Vasculitis #Rheumatology ... #Management